Hi, it started by an occasional pain in hands around a year ago and started medications for rheumatoid then became worse and changed doctors. I have been diagnosed by many doctors many different diseases. Some doctors say I have ankylosing spondylitis, others say rheumatoid (even though my r.f is normal), and others say I do not suffer of anything but some stiffness, and I should lose some weight. I have been taking cosentyx for about 8-9 months with salazopyrin and other things. I started to feel weaker and more symptoms started to appear like cracking sounds and feeling of the joints gliding on each other or others doing friction with each other after I started the medication. My question is if I really have nothing, what is the effect of the medications and the cosentyx on my body? And might it be causing me those symptoms.

Dr. Anuj NigamOrthopedic Doctor6yrs exp

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Hello Mr. lybrate-user. Rheumatoid arthritis and ankylosing spondylitis belong to inflammatory arthritis diseases and are usually presented later in life. These are diseases going into generations. Rf or ra factor can be normal in these diseases as it is not a specific test. Your rf can be normal and yet you can have severe disease. These diseases are progressive, once started they will progress and not be healed. However latest treatments provide an opportunity to slow down the progress of these type of arthritis. (the treatment you are taking) what you are experiencing is initial stages of such disease as per details provided by you. I would recommend to visit a rheumatologist for change or rather updated treatment. Being at young age it is the right time to start accurate treatments. A change in routine lifestyle with involvement of excercises and diet modification will help betterment of your joints and the symptoms and sounds you are getting in joints will heal up. Do connect for more details. Please do give a feedback.  

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